Now showing items 1-2 of 2

    • EMT and MET: necessary or permissive for metastasis? 

      Jolly, Mohit Kumar; Ware, Kathryn E.; Gilja, Shivee; Somarelli, Jason A.; Levine, Herbert (2017)
      Epithelial-to-mesenchymal transition (EMT) and its reverse mesenchymal-to-epithelial transition (MET) have been suggested to play crucial roles in metastatic dissemination of carcinomas. These phenotypic transitions between ...
    • Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding? 

      Jolly, Mohit Kumar; Tripathi, Satyendra C.; Somarelli, Jason A.; Hanash, Samir M.; Levine, Herbert (2017)
      Phenotypic plasticity, the ability of cells to reversibly alter their phenotypes in response to signals, presents a significant clinical challenge to treating solid tumors. Tumor cells utilize phenotypic plasticity to evade ...