Browsing by Subject "NADPH bioavailability"
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Improvement of NADPH bioavailability in Escherichia coli through the use of phosphofructokinase deficient strains (2013)NADPH-dependent reactions play important roles in production of industrially valuable compounds. In this study, we used phosphofructokinase (PFK)-deficient strains to direct fructose-6-phosphate to be oxidized through the pentose phosphate pathway (PPP) to increase NADPH generation. pfkA or pfkB single deletion and double-deletion strains were tested ...