Browsing by Subject "13C Metabolic Flux Analysis"
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Mapping tumor metabolism: from personalized multiobjective metabolic flux analysis to intercellular metabolite transport via exosomes (2016-12-02)Departure from healthy and tightly-regulated metabolism is an emerging hallmark of cancer that facilitates tumorigenic characteristics of uncontrolled proliferation, metastasis, and resistance to chemotherapy. Our aim is to elucidate underlying mechanisms of metabolic shifts that satisfy enhanced energetic and biochemical demands of cancer cells. ...