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Title:
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Synthetic studies toward the total synthesis of (+)-anthramycin total syntheses of (+)-neothramycins A and B |
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Author:
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Lin, Shao-Cheng |
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Advisor:
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Fukuyama, T. |
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Abstract:
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Through the serendipitous discovery of a palladium catalyzed conversion of ethylthiol esters to their corresponding aldehydes, the pyrrolo (1,4) benzodiazepine systems found in (+)-anthramycin 1a* and (+)-neothramycins A 2a and B 2b have been constructed from the diethylthiol esters 3 and 4 respectively.
A key intermediate 5 for the total synthesis of (+)-anthramycin and a facile route to (+)-neothramycins A and B are thus provided. ftn*Please refer to dissertation for diagrams. |
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Citation:
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Lin, Shao-Cheng. "Synthetic studies toward the total synthesis of (+)-anthramycin total syntheses of (+)-neothramycins A and B." Doctoral Thesis, Rice University, ETD http://hdl.handle.net/1911/16364. |
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Citable link to this page:
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http://hdl.handle.net/1911/16364 |
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Date:
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1990 |
